个人简介

  本人博士毕业于中山大学材料物理与化学专业，长期致力于肿瘤微环境响应纳米药物用于抗肿瘤免疫治疗的研究，探索增敏免疫治疗和降低免疫治疗相关副反应的机制。目前作为访问学者在南方科技大学生物医学工程系蒋兴宇教授课题组进行合作，从事微流控制备纳米药物用于增强抗肿瘤免疫治疗工作。近五年以第一（含共一）作者身份在Advanced Science, Small, Science Advances, ACS Applied Materials & Interfaces, Biomaterials Science, Nano Research, Drug Resistance Updates等期刊发表学术论文7篇，主持广东省基金1项。

学历：博士

职位：访问学者（博士后）

教育背景

    2014/09-2019/06  博士  中山大学   材料物理与化学

    2010/09-2014/06  本科  中山大学   高分子材料与工程

研究方向

肿瘤微环境响应纳米药物；抗肿瘤免疫治疗；微流自组装

工作经历

    2020/07-2023/06  深圳市人民医院             博士后

    2019/07-2020/06  广州康臣药业有限公司，药研中心  高级工程师

代表性论文

[1] Zhenwei Su#; Shaowei Dong#; Yao Chen; Tuxiong Huang; Bo Qin; Qinhe Yang; Xingyu Jiang*; Chang Zou*. Microfluidics-enabled nano-vesicle delivers CD47/PD-L1 antibodies to enhance anti-tumor immunity and reduce immunotoxicity in lung adenocarcinoma, Advanced Science, 2023, 2206213. （IF=17.521）

[2] Zhenenwei Su#; Zecong Xiao#; Yong Wang; Jinsheng Huang; Yongcheng An; Xu Wang; Xintao Shuai*; Codelivery of anti-PD-1 antibody and paclitaxel with matrix metalloproteinase and pH dual-sensitive micelles for enhanced tumor chemoimmunotherapy, Small, 2020, 16: 1906832. （IF=15.153）

[3] Zecong Xiao#; Zhenwei Su#; Shisong Han#; Jinsheng Huang; Liteng Lin; Xintao Shuai*; Dual pH-sensitive nanodrug blocks PD-1 immune checkpoint and uses T cells to deliver NF-κB inhibitor for antitumor immunotherapy, Science Advances, 2020, 6: eaay7785. （IF=14.957）

[4] Zhenwei Su#; Zecong Xiao#; Jinsheng Huang; Yong Wang; Yongcheng An; Hong Xiao; Yuan Peng; Pengfei Pang; Shisong Han*; Xintao Shuai*; Dual-sensitive PEG-sheddable nanodrug hierarchically incorporating PD-L1 antibody and zinc phthalocyanine for improved immuno-photodynamic therapy, ACS Applied Materials & Interfaces, 2021, 13(11): 12845-12856. （IF=10.383）

[5] Zhenwei Su#; Yongmin Xu#; Yong Wang; Wanqi Shi; Shisong Han*; Xintao Shuai*; A pH and reduction dual-sensitive polymeric nanomicelle for tumor microenvironment triggered cellular uptake and controlled intracellular drug release, Biomaterials Science, 2019, 7(9): 3821-3831. （IF=7.590）

[6] Yiru Wang#; Tinghui Yin#; Zhenwei Su#; Chen Qiu; Yong Wang; Rongqin Zheng; Meiwan Chen; Xintao Shuai*; Highly uniform ultrasound-sensitive nanospheres produced by a pH-induced micelle-to-vesicle transition for tumor-targeted drug delivery, Nano Research, 2018, 11(7): 3710-3721. （IF=10.269）

[7] Zhenwei Su#, Shaowei Dong#, Shan-Chao Zhao#, Kaisheng Liu, Yao Tan, Xingyu Jiang, Yehuda G. Assaraf, Bo Qin*, Zhe-Sheng Chen*, Chang Zou*, Novel nanomedicines to overcome cancer multidrug resistance. Drug Resistance Updates, 2021, 58，100777. （IF=22.841）