蒋兴宇课题组

    Prof.Jiang's Group    课题组网页

一、微流控芯片与生物分析

核心:微流控结合纳米材料,用于超高灵敏检测、即时诊断 (POCT)、单分子分析

  1. Zhang JJ, Chai FL, Li JA, Wang SJ, Zhang SL, Li FG, Liang AX, Luo AQ, Wang D, Jiang XY. Weakly Ionized Gold Nanoparticles Amplify Immunoassays for Ultrasensitive POCT. Science Advances, 2024, 10 (28): eadn5698.
  2. Yang MZ, Zhang W, Jiang XY. Skiving Stacked Sheets of Paper Into Test Paper for Rapid and Multiplexed Assay. Science Advances, 2017, 3 (12): eaao4862.
  3. Li Z, Li F, Wang Z, Jiang XY. Unlocking Zeptomolar Single-Molecule Detection by Synergizing Digital Microfluidics and Digital CRISPR. JACS, 2025, 147 (12): 4583-4592.
  4. Chai FL, Wang D, Jiang XY. MOF@Gold Nanoparticles Enables POCT Comparable to Chemiluminescence. Anal Chem, 2026, 98 (5): 2345-2353.
  5. Sun JS, Xianyu YL, Jiang XY. Point-of-care Biochemical Assays Using Gold Nanoparticle-implemented Microfluidics. Chem Soc Rev, 2014, 43 (17): 6239-6253.


二、纳米生物医学与抗菌 / 肿瘤治疗

核心:纳米材料(金簇、MOF)用于抗菌、肿瘤靶向、药物递送

  1. Tang H, Zhao X, Jiang XY. Chemically Tailored Anionic Antibiotic Adjuvants Overcome Carbapenem Resistance. Science Advances, 2025, 11 (12): eadz0574.
  2.  Chen M, Zhang JJ, Qi J, Dong RH, Liu HM, Wu DC, Shao HW, Jiang XY. Boronic Acid-Decorated Multivariate Photosensitive Metal–Organic Frameworks for Combating Multi-Drug-Resistant Bacteria. ACS Nano, 2022, 16 (5): 7732–7744.
  3. Wang P, Zhang LM, Zheng WF, Cong LM, Guo ZR, Xie YZY, Wang L, Tang RB, Feng Q, Hamada Y, Gonda K, Hu ZJ, Wu XC, Jiang XY. Thermo-triggered Release of CRISPR-Cas9 by Lipid-gold Nanoparticles for Tumor Therapy. Angew Chem Int Ed, 2018, 57 (5): 1491-1496.
  4. Zhao YY, Chen ZL, Zhang LM, Jiang XY. Synergy of Non-antibiotic Drugs and Pyrimidinethiol on Gold Nanoparticles Against Superbugs. JACS, 2013, 135 (35): 12940-12943.


三、柔性电子与生物电子器件

核心:液态金属、电子纹身、可降解电子血管、人机接口

  1. Tang LX, Shang J, Jiang XY. Multilayered Electronic Transfer Tattoo That Can Enable the Crease Amplification Effect. Science Advances, 2021, 7 (31): eabe3778.
  2. Wu Y, Cheng JH, Qi J, Hang C, Dong RH, Low BC, Yu H, Jiang XY. 3D Liquid Metal-based Neuro-interfaces for Human Hippocampal Organoids. Nature Communications, 2024, 15 (1): e4047.
  3. Yang S, Cheng J,Shang J, Hang C, Qi J, Zhong L, Rao Q, He L, Liu C, Ding L, Zhang M, Chakrabarty S, Jiang XY. Stretchable Surface Electromyography Electrode Array Patch for Tendon Location and Muscle Injury Prevention. Nature Communications ,2023, 14, 6494
  4. Chen S, Guo Z, Lu B, Jiang XY. Wearable Device for Continuous Immunoassay Monitoring of C-Peptide. Science Advances, 2025, 11 (29): eadw2182.
  5. Qi J, Yang SJ, Jiang YZ, Cheng JH, Wang SJ, Rao QY, Jiang XY. Liquid Metal–Polymer Conductor-Based Conformal Cyborg Devices. Chemical Reviews, 2024, 124 (5): 2081-2137.
  6. Cheng SY, Hang C, Ding L, Jia L, Tang LX, Mou L, Qi J, Dong RH, Zheng WF, Zhang Y, Jiang XY. Electronic Blood Vessel. Matter, 2020, 3 (6): 1919-1934.
  7. Liu C, Yang S, Zhang J, Yu K, Liu Y, Chen S, Jiang XY. Stretchable Patch for Multimodal Theranostic Human-Machine Interface. Adv Healthcare Mater, 2025, 14 (7): e03353.


四、DNA / 生物大分子存储与逻辑

核心:DNA 分子存储、生物计算

  1. Li J, Mao C, Wang S, Jiang XY. A Compact Cassette Tape for DNA-based Data Storage. Science Advances, 2025, 11 (37): eady3406.
  2. Zhang Y, Liu Y, Miao L, Zhu H, Jiang XY, Zhang H, Fan C, Liu K. Liquid crystal-guided DNA information storage: Nondestructive recovery and long-term preservation. Science Advances, 2025, 11 (39), eadu3957
  3. Zhang Y, Guo YM, Liu DB, Jiang XY. Nanomaterials for Ultrasensitive Protein Detection. Adv Mater, 2013, 25 (28): 3802-3819
  4. Qu WS, Liu YY, et al. Copper-mediated Amplification Allows Readout of Immunoassays by The Naked Eye. Angew Chem Int Ed, 2012, 51 (22): 5470-5473.
  5. Liu DB, Chen WW, Zhang Y, Jiang XY. Resettable, Multi-readout Logic Gates Based on Reversible Aggregation of Gold Nanoparticles. Angew Chem Int Ed, 2011, 50 (18): 4103-4107.