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纳米生物医学与抗菌/肿瘤治疗
2026
494 Zhang, P.; Cha, R.; Luo, H.; Li, C.; Hao, W.; Zhang, C.; Lin, Q.; Si, Y.; Wang, X.; Jiang, X. Gold Nanoparticles Regulate Gut Microbiota and Immune Responses for Overcoming Iron Supplementation Side Effects in Anemia Therapy. ACS Nano 2026, 20, 11, 9572-9588
492 Qi, J.; Zhu, Y.; Hang, C.; Tang, H.; Zhang, L.; Jiang, X. Surface curvature-directed in situ synthesis of ultrathin 2D MOFs on liquid metals for antibacterial applications. Chemical Science 2026, 17, 6746-6754
490 Zhu, Y.; Tang, H.; Jiang, X. Multiscale Aggregation Materials for Disease Therapy and Bioanalysis. Chemical Communications 2026, DOI: 10.1039/D5CC05311K
2025
485 Tang, H.; Zhao, X.; Jiang, X. Chemically tailored anionic antibiotic adjuvants targeting divalent cations to overcome carbapenem resistance in gram-negative bacteria. Science Advances 2025, 11, eadz0574
477 Si, Y.; Cha, R.; Zhang, P.; Zhou, F.; Jiang, X. CD-MOF Based pH/ROS Sensitive 5-ASA Delivery System for Ulcerative Colitis Therapy. Advanced Healthcare Materials 2025, 2501160.
475 Zhang, P.; Cha, R.; Si, Y.; Luo, H.; Lin, Q.; Qin, J.; Tang, H.; Zhou, F.; Wang, X.; Jiang, X. Au&WO3 Heterojunctions against Multidrug-Resistant Bacteria. Nano Today 2025, 64, 102813.
474 Zhang, C.; Wang, C.; Cha, R.; Meng, Q.; Hu, Z.; Sun, Y.; Li, Z.; Xiao, M.; Zhang, Y.; Jiang, X. Rapid Preparation of Collagen/Red Blood Cell Membrane Tubes for Stenosis-Free Vascular Regeneration. ACS Nano 2025, 19, 3293-3311
472 Xiao, F.; Zhu, Y.; Chen, Y.; Li, Q.; Qi, J.; Qin, Z.; Zhao, X.; Pang, Z.; Tang, H.; Xie, J.; Jiang, X. Inhibition of Post-Surgical Tumor Recurrence by 3-Bromopyruvate-Conjugated Gold Nanoclusters via MAPK and PI3K-Akt Pathways. Nano Letters 2025, 25, 24, 9560-9569
471 Qi, J.; Xie, C.; Chen, M.; Hang, C.; Zhang, L.; Jiang, X. Precision-Controlled Sequential Drug Release via Electrochemical Corrosion of Liquid Metal Nanoparticles. Science Advances 2025, 11, eadw6986.
469 Li, X.; Qin, Z.; Wang, S.; Zhang, L.; Jiang, X. Microfluidics-Assembled Nanovesicles for Nucleic Acid Delivery. Accounts of Chemical Research 2025, 58, 570-582.
2024
460 Zhang, C.; Cha, R.; Long, K.; Liu, Y.; Dong, Y.; Zhang, Y.; Wang, X.; Jiang, X. Functionalized Iron Oxide Nanoparticles for Both Dual-Modal Imaging and Erythropoiesis. ACS Applied Materials & Interfaces 2024, 16, 68905-68917.
457 Wu, Y.; Cheng, J.; Qi, J.; Hang, C.; Dong, R.; Low, B. C.; Yu, H.; Jiang, X. Three-Dimensional Liquid Metal-Based Neuro-Interfaces for Human Hippocampal Organoids. Nature Communications 2024, 15, 4047.
452 Ma, Y.; Li, Z.; Luo, Y.; Chen, Y.; Ma, L.; Liu, X.; Xiao, J.; Huang, M.; Li, Y.; Jiang, H.; Wang, M.; Wang, X.; Li, J.; Kong, J.; Shi, P.; Yu, H.; Jiang, X.; Guo, Q. Biodegradable Microembolics with Nanografted Polyanions Enable High-Efficiency Drug Loading and Sustained Deep-Tumor Drug Penetration for Locoregional Chemoembolization Treatment. ACS Nano 2024, 18, 18211-18229.
449 Hu, Y.; Tang, H.; Xu, N.; Kang, X.; Wu, W.; Shen, C.; Lin, J.; Bao, Y.; Jiang, X.; Luo, Z. Adhesive, Flexible, and Fast Degradable 3D‐printed Wound Dressings with a Simple Composition. Advanced Healthcare Materials 2024, 13, 2302063.
447 Dong, R.; Chen, M.; Jia, Y.; Tang, H.; Xiong, Z.; Long, Y.; Jiang, X. An in situ Dressing Material Containing a Multi‐armed Antibiotic for Healing Irregular Wounds. Aggregate 2024, 5, e493.
2023
445 Zhou, T.; Zha, M.; Tang, H.; Li, K.; Jiang, X. Controlling NIR-II Emitting Gold Organic/Inorganic Nanohybrids with Tunable Morphology and Surface PEG Density for Dynamic Visualization of Vascular Dysfunction. Chemical Science 2023, 14, 8842-8849.
444 Zhao, X.; Liu, S.; Jiang, X. Leveraging Bimetallic Nanoparticles to Synergistically Enhance the Efficacy of Antibiotics against Carbapenem-Resistant Bacteria. Science China Materials 2023, 66, 2885-2892.
443 Zhang, Z.; Chen, Y.; Gao, J.; Yang, M.; Zhang, D.; Wang, L.; Zhang, T.; Cao, Q.; Mwangi, J.; He, C.; Li, Y.; Liu, X.; Jiang, X.; Kamau, P. M.; Lai, R. Orientational Nanoconjugation with Gold Endows Marked Antimicrobial Potential and Drugability of Ultrashort Dipeptides. Nano Letters 2023, 23, 11874-11883.
442 Zhang, L.; Lin, Y.; Li, S.; Guan, X.; Jiang, X. In situ Reprogramming of Tumor‐associated Macrophages with Internally and Externally Engineered Exosomes. Angewandte Chemie International Edition 2023, 62, e202217089.
441 Zhang, C.; Cha, R.; Wang, C.; Chen, X.; Li, Z.; Xie, Q.; Jia, L.; Sun, Y.; Hu, Z.; Zhang, L.; Zhou, F.; Zhang, Y.; Jiang, X. Red Blood Cell Membrane-Functionalized Nanofibrous Tubes for Small-Diameter Vascular Grafts. Biomaterials 2023, 297, 122124.
437 Wang, M.; Cha, R.; Hao, W.; Jiang, X. Nanocrystalline Cellulose Modulates Dysregulated Intestinal Barriers in Ulcerative Colitis. ACS Nano 2023, 17, 18965-18978.
436 Wang, L.; Zheng, W.; Zhong, L.; Yang, Y.; Chen, Y.; Hou, Q.; Yu, P.; Jiang, X. Phenylboronic Acid-Modified Gold Nanoclusters as a Nanoantibiotic to Treat Vancomycin-Resistant Enterococcus faecalis-Caused Infections. ACS Nano 2023, 17, 19685-19695.
433 Tang, H.; Qin, H.; He, S.; Li, Q.; Xu, H.; Sun, M.; Li, J.; Lu, S.; Luo, S.; Mao, P.; Han, P.; Song, L.; Tong, Y.; Fan, H.; Jiang, X. Anti‐coronaviral Nanocluster Restrain Infections of SARS‐CoV‐2 and Associated Mutants through Virucidal Inhibition and 3CL Protease Inactivation. Advanced Science 2023, 10, 2207098.
432 Su, Z.; Dong, S.; Chen, Y.; Huang, T.; Qin, B.; Yang, Q.; Jiang, X.; Zou, C. Microfluidics‐enabled Nanovesicle Delivers CD47/PD‐L1 Antibodies to Enhance Antitumor Immunity and Reduce Immunotoxicity in Lung Adenocarcinoma. Advanced Science 2023, 10, 2206213.
418 Chai, F.; Wang, D.; Shi, F.; Zheng, W.; Zhao, X.; Chen, Y.; Mao, C.; Zhang, J.; Jiang, X. Dual Functional Ultrasensitive Point-of-Care Clinical Diagnosis Using Metal-Organic Frameworks-Based Immunobeads. Nano Letters 2023, 23, 9056-9064.
416 Bi, S.; Qi, J.; Zhang, W.; Jiang, X. A Liquid Metal Dressing for Anti-Inflammatory and Anti-Infection Applications to Treat Diabetic Wounds. Chemical Communications 2023, 59, 8420-8423.
415 Bi, S.; Hang, C.; Qi, J.; Zhang, W.; Jiang, X. Green Synthesis of Liquid Metal‐doped Carbon Dots for Treating Multidrug‐resistant Gram‐negative Bacteria. Advanced Biology 2023, 7, 2200297.
2022
413 Zhou, T.; Jiang, X. Modulating Luminescence and Assembled Shapes of Ultrasmall Au Nanoparticles towards Hierarchical Information Encryption. Chemical Science 2022, 13, 12107-12113.
411 Zhao, X.; Tang, H.; Jiang, X. Deploying Gold Nanomaterials in Combating Multi-Drug-Resistant Bacteria. ACS Nano 2022, 16, 10066-10087.
406 Wang, M.; Cha, R.; Hao, W.; Du, R.; Zhang, P.; Hu, Y.; Jiang, X. Nanocrystalline Cellulose Cures Constipation via Gut Microbiota Metabolism. ACS Nano 2022, 16, 16481-16496.
404 Wang, L.; Zheng, W.; Zhong, L.; Yang, Y.; Li, S.; Li, Q.; Jiang, X. Aminophenol-Modified Gold Nanoparticles Kill Bacteria with Minimal Ototoxicity. Chemical Communications 2022, 58, 2842-2845.
403 Wang, L.; Zheng, W.; Li, S.; Zhong, L.; Jiang, X. Aminophenol-Decorated Gold Nanoparticles for Curing Bacterial Infections. Nano Letters 2022, 22, 3576-3582.
402 Wang, L.; Zheng, W.; Hou, Q.; Zhong, L.; Li, Q.; Jiang, X. Breathable and Stretchable Dressings for Accelerating Healing of Infected Wounds. Advanced Healthcare Materials 2022, 11, 2201053.
401 Wang, D.; Dong, R.; Wang, X.; Jiang, X. Flexible Electronic Catheter Based on Nanofibers for the in vivo Elimination of Circulating Tumor Cells. ACS Nano 2022, 16, 5274-5283.
398 Ren, N.; Hang, C.; Liu, X.; Jiang, X. Printable Metal-Polymer Conductors for Local Drug Delivery. Nano Letters 2022, 22, 7554-7562.
397 Pang, Z.; Yan, W.; Yang, J.; Li, Q.; Guo, Y.; Zhou, D.; Jiang, X. Multifunctional Gold Nanoclusters for Effective Targeting, near-Infrared Fluorescence Imaging, Diagnosis, and Treatment of Cancer Lymphatic Metastasis. ACS Nano 2022, 16, 16019-16037.
379 Chen, M.; Zhang, J.; Qi, J.; Dong, R.; Liu, H.; Wu, D.; Shao, H.; Jiang, X. Boronic Acid-Decorated Multivariate Photosensitive Metal-Organic Frameworks for Combating Multi-Drug-Resistant Bacteria. ACS Nano 2022, 16, 7732-7744.
2021
373 Zheng, W.; Jia, Y.; Zhao, Y.; Zhang, J.; Xie, Y.; Wang, L.; Zhao, X.; Liu, X.; Tang, R.; Chen, W.; Jiang, X. Reversing Bacterial Resistance to Gold Nanoparticles by Size Modulation. Nano Letters 2021, 21, 1992-2000.
364 Wang, L.; Yang, J.; Li, S.; Li, Q.; Liu, S.; Zheng, W.; Jiang, X. Oral Administration of Starting Materials for in vivo Synthesis of Antibacterial Gold Nanoparticles for Curing Remote Infections. Nano Letters 2021, 21, 1124-1131.
362 Wang, L.; Hou, Q.; Zheng, W.; Jiang, X. Fluorescent and Antibacterial Aminobenzeneboronic Acid (ABA)-Modified Gold Nanoclusters for Self-Monitoring Residual Dosage and Smart Wound Care. ACS Nano 2021, 15, 17885-17894.
359 Tang, H.; Li, Q.; Yan, W.; Jiang, X. Reversing the Chirality of Surface Ligands Can Improve the Biosafety and Pharmacokinetics of Cationic Gold Nanoclusters. Angewandte Chemie International Edition 2021, 60, 13829-13834.
358 Su, Z.; Dong, S.; Zhao, S.; Liu, K.; Tan, Y.; Jiang, X.; Assaraf, Y.; Qin, B.; Chen, Z.; Zou, C. Novel Nanomedicines to Overcome Cancer Multidrug Resistance. Drug Resistance Updates 2021, 58, 100777.
356 Pang, Z.; Li, Q.; Jia, Y.; Yan, W.; Qi, J.; Guo, Y.; Hu, F.; Zhou, D.; Jiang, X. Controlling the Pyridinium-Zwitterionic Ligand Ratio on Atomically Precise Gold Nanoclusters Allowing for Eradicating Gram-Positive Drug-Resistant Bacteria and Retaining Biocompatibility. Chemical Science 2021, 12, 14871-14882.
2020
327 Xie, Y.; Yang, J.; Zhang, J.; Zheng, W.; Jiang, X. Activating the Antibacterial Effect of 4,6‐diamino‐2‐pyrimidinethiol‐modified Gold Nanoparticles by Reducing Their Sizes. Angewandte Chemie International Edition 2020, 59, 23471-23475.
323 Wang, L.; Zheng, W.; Jiang, X. Benzeneselenol-Modified Gold Nanoclusters for Cancer Therapy. Chemical Communications 2020, 56, 6664-6667.
321 Wang, L.; Li, S.; Yin, J.; Yang, J.; Li, Q.; Zheng, W.; Liu, S.; Jiang, X. The Density of Surface Coating Can Contribute to Different Antibacterial Activities of Gold Nanoparticles. Nano Letters 2020, 20, 5036-5042.
2019
299 Yang, X.; Wei, Q.; Shao, H.; Jiang, X. Multivalent Aminosaccharide-Based Gold Nanoparticles as Narrow-Spectrum Antibiotics in vivo. ACS Applied Materials & Interfaces 2019, 11, 7725-7730.
294 Sun, Z.; Zheng, W.; Zhu, G.; Lian, J.; Wang, J.; Hui, P.; He, S.; Chen, W.; Jiang, X. Albumin Broadens the Antibacterial Capabilities of Nonantibiotic Small Molecule-Capped Gold Nanoparticles. ACS Applied Materials & Interfaces 2019, 11, 45381-45389.
286 Li, J.; Cha, R.; Zhao, X.; Guo, H.; Luo, H.; Wang, M.; Zhou, F.; Jiang, X. Gold Nanoparticles Cure Bacterial Infection with Benefit to Intestinal Microflora. ACS Nano 2019, 13, 5002-5014.
2018
264 Xie, Y.; Liu, Y.; Yang, J.; Liu, Y.; Hu, F.; Zhu, K.; Jiang, X. Gold Nanoclusters for Targeting Methicillin‐resistant Staphylococcus aureus in vivo. Angewandte Chemie International Edition 2018, 57, 3958-3962.
262 Wang, P.; Zhang, L.; Zheng, W.; Cong, L.; Guo, Z.; Xie, Y.; Wang, L.; Tang, R.; Feng, Q.; Hamada, Y.; Gonda, K.; Hu, Z.; Wu, X.; Jiang, X. Thermo‐triggered Release of CRISPR‐Cas9 System by Lipid‐encapsulated Gold Nanoparticles for Tumor Therapy. Angewandte Chemie International Edition 2018, 57, 1491-1496.
277 Zhao, X.; Jia, Y.; Li, J.; Dong, R.; Zhang, J.; Ma, C.; Wang, H.; Rui, Y.; Jiang, X. Indole Derivative-Capped Gold Nanoparticles as an Effective Bactericide in vivo. ACS Applied Materials & Interfaces 2018, 10, 29398-29406.
2017
215 Lei, Y.; Tang, L.; Xie, Y.; Xianyu, Y.; Zhang, L.; Wang, P.; Hamada, Y.; Jiang, K.; Zheng, W.; Jiang, X. Gold Nanoclusters-Assisted Delivery of NGF siRNA for Effective Treatment of Pancreatic Cancer. Nature Communications 2017, 8, 15130.