个人简介：

杨用，现任南方科技大学生物医学工程系副研究员，主要研究方向为生化分析与纳米生物医学。先后主持了3项国家级以及2项省部级科研项目，在Angew Chem Int Ed、Chem Rev、Anal Chem、Chem Commun、JBC等国际知名学术期刊发表论文20余篇。成功入选“广东特支计划”青年拔尖人才以及中国科学院青年创新促进会会员，并获得“深圳市海外高层次人才”、“广东省科学技术奖二等奖”、“深圳市科学技术奖自然科学奖二等奖”等荣誉。

学历：博士

职位：高级实验师

教育背景：

2003- 2009年,中国科学技术大学, 博士(细胞生物学)

1999- 2003年,湖北师范大学, 学士(生物科学)

研究方向

1. 生化分析与分子诊断

2. 纳米生物医学

工作经历

2018-至今，南方科技大学，研究副教授

2009-2018, 中国科学院深圳先进技术研究院, 助理研究员/副研究员

2017–2018, 香港大学, 访问学者

2006–2007, Morehouse School of Medicine,访问学者

代表性论文：

[1] Yang Y., Chen Y., Tang H., Zong N., Jiang X. Y.* Microfluidics for Biomedical Analysis, Small Methods, 2019, 1900451.

[2] Li Y.Y., Yang Y.,* Zhang C.Y.* Visualization and Quantification of Sortase Activity at the Single-Molecule Level via Transpeptidation-Directed Intramolecular Förster Resonance Energy Transfer. Anal. Chem., 2018, 90, 13007-13012. (Nature Index article)

[3] Xu A. J., Yang Y.,* Zhang C.Y.* Transpeptidation-directed intramolecular bipartite tetracysteine display for sortase activity assay. Chem. Commun., 2018, 54, 8116-8119. (Nature Index article)

[4] Yang Y., Liang Y., Zhang C.Y.* Label-Free and Homogenous Detection of Caspase-3-Like Proteases by Disrupting Homodimerization-Directed Bipartite Tetracysteine Display. Anal. Chem., 2017, 89, 4055-4061. (Nature Index article)

[5] Zhou J., Yang Y., Zhang C.Y.* Toward Biocompatible Semiconductor Quantum Dots: From Biosynthesis and Bioconjugation to Biomedical Application. Chem. Rev., 2015, 115, 11669-11717. (SCI, IF=52.613).

[6] Wang L. J.,† Yang Y.,† Zhang C.Y.* Phosphorylation-directed assembly of a single quantum dot based nanosensor for protein kinase assay. Anal. Chem., 2015, 87, 4696-4703. (Nature Index article)

[7] Yang Y., Zhang C.Y.* Visualizing and Quantifying Protein PolySUMOylation at the Single-Molecule Level. Anal. Chem., 2014, 86, 967-972. (Nature Index article, Editors’ Highlight)

[8] Ma F.,† Yang Y.,† Zhang C.Y.* Ultrasensitive Detection of Transcription Factors Using Transcription-Mediated Isothermally Exponential Amplification-Induced Chemiluminescence. Anal. Chem., 2014, 86, 6006-6011. (Nature Index article)

[9] Yang Y., Zhang C.Y.* Simultaneous measurement of SUMOylation using SNAP/CLIP-tag-mediated translation at the single-molecule level. Angew. Chem. Int. Ed., 2013, 52, 691-694. (Nature Index article, IF=12.102)

[10] Zhou J.,† Yang Y.,† Zhang C.Y.* A low-temperature solid-phase method to synthesize highly fluorescent carbon nitride dots with tunable emission. Chem. Commun., 2013, 49, 8605-8607. (Nature Index article, Back cover)

[11] Yang Y., Zhang C.Y.* Sensitive Detection of Intracellular Sumoylation via SNAP Tag-Mediated Translation and RNA Polymerase-Based Amplification. Anal. Chem., 2012, 84, 1229-1234. (Nature Index article)

[12] Yang Y., Wu F., Ward T., Yan F., Wu Q., Wang Z.Y., McGlothen T., Peng W., You T. P., Sun M. K., Cui T. X., Hu R. M., Dou Z., Zhu J. D., Xie W., Rao Z. H., Yao X. B.* Phosphorylation of HsMis13 by aurora B is essential for assembly of functional kinetochore. J. Biol. Chem., 2008, 283, 26726-26736.